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2009

  • Shi, J.; Kim, Y.-S.; Zhai, S.; Liu, Z.; Chen, X.; Liu, S., Improving Tumor Uptake and Pharmacokinetics of 64Cu-Labeled Cyclic RGD Peptide Dimers with Gly3 and PEG4 Linkers.

    Bioconjugate Chemistry 2009, 20, (4), 750-759.

  • Liu, Z.; Yan, Y.; Liu, S.; Wang, F.; Chen, X., 18F, 64Cu, and 68Ga Labeled RGD-Bombesin Heterodimeric Peptides for PET Imaging of Breast Cancer.

    Bioconjugate Chemistry 2009, 20, (5), 1016-1025.

  • Liu, D.; Overbey, D.; Watkinson, L.; Giblin, M. F., Synthesis and Characterization of an 111In-Labeled Peptide for the in Vivo Localization of Human Cancers Expressing the Urokinase-Type Plasminogen Activator Receptor (uPAR).

    Bioconjugate Chemistry 2009, 20, (5), 888-894.

  • Levy, S. G.; Jacques, V.; Zhou, K. L.; Kalogeropoulos, S.; Schumacher, K.; Amedio, J. C.; Scherer, J. E.; Witowski, S. R.; Lombardy, R.; Koppetsch, K., Development of a Multigram Asymmetric Synthesis of 2-(R)-2-(4,7,10-Tris tert-Butylcarboxymethyl-1,4,7,10-tetraazacyclododec-1-yl)-pentanedioic Acid, 1-tert-Butyl Ester, (R)-tert-Bu4-DOTAGA(1).

    Organic Process Research & Development 2009 13, (3), 535-542.

  • Levashova, Z.; Backer, M. V.; Horng, G.; Felsher, D.; Backer, J. M.; Blankenberg, F. G., SPECT and PET Imaging of EGF Receptors with Site-Specifically Labeled EGF and Dimeric EGF.

    Bioconjugate Chemistry 2009, 20, (4), 742-749.

  • Josan, J. S.; Morse, D. L.; Xu, L.; Trissal, M.; Baggett, B.; Davis, P.; Vagner, J.; Gillies, R. J.; Hruby, V. J., Solid-Phase Synthetic Strategy and Bioevaluation of a Labeled δ-Opioid Receptor Ligand Dmt-Tic-Lys for In Vivo Imaging.

    Organic Letters 2009, 11, (12), 2479-2482.

  • Hoang, B.; Lee, H.; Reilly, R. M.; Allen, C., Noninvasive Monitoring of the Fate of 111In-Labeled Block Copolymer Micelles by High Resolution and High Sensitivity MicroSPECT/CT Imaging.

    Molecular Pharmaceutics 2009, 6, (2), 581-592.

  • Blom, E.; Langstrom, B.; Velikyan, I., 68Ga-Labeling of Biotin Analogues and their Characterization.

    Bioconjugate Chemistry 2009, 20, (6), 1146-1151.

2008

  • Yang, C.-T.; Kim, Y.-S.; Wang, J.; Wang, L.; Shi, J.; Li, Z.-B.; Chen, X.; Fan, M.; Li, J.-J.; Liu, S., 64Cu-Labeled 2-(Diphenylphosphoryl)ethyldiphenylphosphonium Cations as Highly Selective Tumor Imaging Agents: Effects of Linkers and Chelates on Radiotracer Biodistribution Characteristics.

    Bioconjugate Chemistry 2008, 19, (10), 2008-2022.

  • Wu, Y.; Zhou, Y.; Ouari, O.; Woods, M.; Zhao, P.; Soesbe, T. C.; Kiefer, G. E.; Sherry, A. D., Polymeric PARACEST Agents for Enhancing MRI Contrast Sensitivity.

    Journal of the American Chemical Society 2008, 130, (42), 13854-13855.

  • Wang, S.; Westmoreland, T. D., Correlation of Relaxivity with Coordination Number in Six-, Seven-, and Eight-Coordinate Mn(II) Complexes of Pendant-Arm Cyclen Derivatives.

    Inorganic Chemistry 2008, 48, (2), 719-727.

  • Tolmachev, V.; Xu, H.; Wallberg, H.; Ahlgren, S.; Hjertman, M.; Sjoberg, A.; Sandstrom, M.; Abrahmsen, L.; Brechbiel, M. W.; Orlova, A., Evaluation of a Maleimido Derivative of CHX-A”DTPA for Site-Specific Labeling of Affibody Molecules.

    Bioconjugate Chemistry 2008, 19, (8), 1579-1587.

  • Schottelius, M.; Berger, S.; Poethko, T.; Schwaiger, M.; Wester, H.-J. r., Development of Novel 68Ga- and 18F-Labeled GnRH-I Analogues with High GnRHR-Targeting Efficiency.

    Bioconjugate Chemistry 2008, 19, (6), 1256-1268.

  • Schlesinger, J.; Koezle, I.; Bergmann, R.; Tamburini, S.; Bolzati, C.; Tisato, F.; Noll, B.; Klussmann, S.; Vonhoff, S.; Wuest, F.; Pietzsch, H.-J.; Steinbach, J., An 86Y-Labeled Mirror-Image Oligonucleotide: Influence of Y-DOTA Isomers on the Biodistribution in Ratsâ€

    Bioconjugate Chemistry 2008, 19, (4), 928-939.

  • Neundorf, I.; Rennert, R.; Franke, J.; Kozle, I.; Bergmann, R., Detailed Analysis Concerning the Biodistribution and Metabolism of Human Calcitonin-Derived Cell-Penetrating Peptides

    Bioconjugate Chemistry 2008, 19, (8), 1596-1603.

  • Natarajan, A.; Gruettner, C.; Ivkov, R.; DeNardo, G. L.; Mirick, G.; Yuan, A.; Foreman, A.; DeNardo, S. J., NanoFerrite Particle Based Radioimmunonanoparticles: Binding Affinity and In Vivo Pharmacokinetics.

    Bioconjugate Chemistry 2008, 19, (6), 1211-1218.

  • Miao, Y.; Gallazzi, F.; Guo, H.; Quinn, T. P., 111In-Labeled Lactam Bridge-Cyclized α-Melanocyte Stimulating Hormone Peptide Analogues for Melanoma Imaging.

    Bioconjugate Chemistry 2008, 19, (2), 539-547.

  • Kim, Y.-S.; Yang, C.-T.; Wang, J.; Wang, L.; Li, Z.-B.; Chen, X.; Liu, S., Effects of Targeting Moiety, Linker, Bifunctional Chelator, and Molecular Charge on Biological Properties of 64Cu-Labeled Triphenylphosphonium Cations.

    Journal of Medicinal Chemistry 2008, 51, (10), 2971-2984.

  • Jarrett, B. R.; Gustafsson, B. r.; Kukis, D. L.; Louie, A. Y., Synthesis of 64Cu-Labeled Magnetic Nanoparticles for Multimodal Imaging.

    Bioconjugate Chemistry 2008, 19, (7), 1496-1504.

  • Huang, S.; Joso, R.; Fuchs, A.; Barner, L.; Smith, S. V., Probing Solid−Liquid Interfaces Using Radiotracer Technology: Characterization of Functionalized Microspheres.

    Chemistry of Materials 2008, 20, (16), 5375-5380.

  • Garrison, J. C.; Rold, T. L.; Sieckman, G. L.; Naz, F.; Sublett, S. V.; Figueroa, S. D.; Volkert, W. A.; Hoffman, T. J., Evaluation of the Pharmacokinetic Effects of Various Linking Group Using the 111In-DOTA-X-BBN(7-14)NH2 Structural Paradigm in a Prostate Cancer Model.

    Bioconjugate Chemistry 2008, 19, (9), 1803-1812.

  • Fukukawa, K.-i.; Rossin, R.; Hagooly, A.; Pressly, E. D.; Hunt, J. N.; Messmore, B. W.; Wooley, K. L.; Welch, M. J.; Hawker, C. J., Synthesis and Characterization of “Core-Shell Star Copolymers for In Vivo PET Imaging Applications.

    Biomacromolecules 2008, 9, (4), 1329-1339.

  • Flavell, R. R.; Kothari, P.; Bar-Dagan, M.; Synan, M.; Vallabhajosula, S.; Friedman, J. M.; Muir, T. W.; Ceccarini, G., Site-Specific 18F-Labeling of the Protein Hormone Leptin Using a General Two-Step Ligation Procedure.

    Journal of the American Chemical Society 2008, 130, (28), 9106-9112.

  • Endres, P. J.; MacRenaris, K. W.; Vogt, S.; Meade, T. J., Cell-Permeable MR Contrast Agents with Increased Intracellular Retention.

    Bioconjugate Chemistry 2008, 19, (10), 2049-2059.

  • Chong, H.-S.; Song, H. A.; Ma, X.; E. Milenic, D.; D. Brady, E.; Lim, S.; Lee, H.; Baidoo, K.; Cheng, D.; Brechbiel, M. W., Novel Bimodal Bifunctional Ligands for Radioimmunotherapy and Targeted MRI.

    Bioconjugate Chemistry 2008, 19, (7), 1439-1447.

  • Chang, M.-Y.; Seideman, J.; Sofou, S., Enhanced Loading Efficiency and Retention of 225Ac in Rigid Liposomes for Potential Targeted Therapy of Micrometastases.

    Bioconjugate Chemistry 2008, 19, (6), 1274-1282.

  • Cescato, R.; Erchegyi, J.; Waser, B.; Piccand, V. r.; Maecke, H. R.; Rivier, J. E.; Reubi, J. C., Design and in Vitro Characterization of Highly sst2-Selective Somatostatin Antagonists Suitable for Radiotargeting.

    Journal of Medicinal Chemistry 2008, 51, (13), 4030-4037.

  • Bigott-Hennkens, H. M.; Junnotula, S.; Ma, L.; Gallazzi, F.; Lewis, M. R.; Jurisson, S. S., Synthesis and in Vitro Evaluation of a Rhenium-Cyclized Somatostatin Derivative Series.

    Journal of Medicinal Chemistry 2008, 51, (5), 1223-1230.

  • Bartlett, D. W.; Colcher, D.; Raubitschek, A. A., Rapid and Efficient Production of Radiolabeled Antibody Conjugates Using Vacuum Diafiltration Guided by Mathematical Modeling.

    Bioconjugate Chemistry 2008, 19, (9), 1927-1937.

  • Bakalova, R.; Zhelev, Z.; Aoki, I.; Masamoto, K.; Mileva, M.; Obata, T.; Higuchi, M.; Gadjeva, V.; Kanno, I., Multimodal Silica-Shelled Quantum Dots: Direct Intracellular Delivery, Photosensitization, Toxic, and Microcirculation Effects.

    Bioconjugate Chemistry 2008, 19, (6), 1135-1142.

2007

  • Zhou, X.-S.; Dong, Z.-R.; Zhang, H.-M.; Yan, J.-W.; Gao, J.-X.; Mao, B.-W., Self-Assembly of a Rh(I) Complex on Au(111) Surfaces and Its Electrocatalytic Activity toward the Hydrogen Evolution Reaction.

    Langmuir 2007, 23, (12), 6819-6826.

  • Yoo, B.; Pagel, M. D., Peptidyl Molecular Imaging Contrast Agents Using a New Solid-Phase Peptide Synthesis Approach.

    Bioconjugate Chemistry 2007, 18, (3), 903-911.

  • Yang, Z.; Zheng, S.; Harrison, W. J.; Harder, J.; Wen, X.; Gelovani, J. G.; Qiao, A.; Li, C., Long-Circulating Near-Infrared Fluorescence Core-Cross-Linked Polymeric Micelles: Synthesis, Characterization, and Dual Nuclear/Optical Imaging.

    Biomacromolecules 2007, 8, (11), 3422-3428.

  • Yang, C.-T.; Li, Y.; Liu, S., Synthesis and Structural Characterization of Complexes of a DO3A-Conjugated Triphenylphosphonium Cation with Diagnostically Important Metal Ions.

    Inorganic Chemistry 2007, 46, (21), 8988-8997.

  • Wilbur, D. S.; Hamlin, D. K.; Chyan, M.-K.; Brechbiel, M. W., Streptavidin in Antibody Pretargeting. 5. Chemical Modification of Recombinant Streptavidin for Labeling with the a-Particle-Emitting Radionuclides 213Bi and 211At.

    Bioconjugate Chemistry 2007, 19, (1), 158-170.

  • Wang, W.; Ke, S.; Kwon, S.; Yallampalli, S.; Cameron, A. G.; Adams, K. E.; Mawad, M. E.; Sevick-Muraca, E. M., A New Optical and Nuclear Dual-Labeled Imaging Agent Targeting Interleukin 11 Receptor Alpha-Chain.

    Bioconjugate Chemistry 2007, 18, (2), 397-402.

  • Wang, J.; Yang, C.-T.; Kim, Y.-S.; Sreerama, S. G.; Cao, Q.; Li, Z.-B.; He, Z.; Chen, X.; Liu, S., 64Cu-Labeled Triphenylphosphonium and Triphenylarsonium Cations as Highly Tumor-Selective Imaging Agents.

    Journal of Medicinal Chemistry 2007, 50, (21), 5057-5069.

  • Sofou, S.; Kappel, B. J.; Jaggi, J. S.; McDevitt, M. R.; Scheinberg, D. A.; Sgouros, G., Enhanced Retention of the a-Particle-Emitting Daughters of Actinium-225 by Liposome Carriers.

    Bioconjugate Chemistry 2007, 18, (6), 2061-2067.

  • Ratnakar, S. J.; Woods, M.; Lubag, A. J. M.; Kovacs, Z.; Sherry, A. D., Modulation of Water Exchange in Europium(III) DOTA-Tetraamide Complexes via Electronic Substituent Effects.

    Journal of the American Chemical Society 2007, 130, (1), 6-7.

  • Pressly, E. D.; Rossin, R.; Hagooly, A.; Fukukawa, K.-i.; Messmore, B. W.; Welch, M. J.; Wooley, K. L.; Lamm, M. S.; Hule, R. A.; Pochan, D. J.; Hawker, C. J., Structural Effects on the Biodistribution and Positron Emission Tomography (PET) Imaging of Well-Defined 64Cu-Labeled Nanoparticles Comprised of Amphiphilic Block Graft Copolymers.

    Biomacromolecules 2007, 8, (10), 3126-3134.

  • Parry, J. J.; Kelly, T. S.; Andrews, R.; Rogers, B. E., In Vitro and in Vivo Evaluation of 64Cu-Labeled DOTA-Linkerâ-Bombesin(7-14) Analogues Containing Different Amino Acid Linker Moieties.

    Bioconjugate Chemistry 2007, 18, (4), 1110-1117.

  • Neves, A. A.; Krishnan, A. S.; Kettunen, M. I.; Hu, D.-e.; de Backer, M. M.; Davletov, B.; Brindle, K. M., A Paramagnetic Nanoprobe To Detect Tumor Cell Death Using Magnetic Resonance Imaging.

    Nano Letters 2007, 7, (5), 1419-1423.

  • Miao, Z.; McCoy, M. R.; Singh, D. D.; Barrios, B.; Hsu, O. L.; Cheal, S. M.; Meares, C. F., Cysteinylated Protein as Reactive Disulfide: An Alternative Route to Affinity Labeling.

    Bioconjugate Chemistry 2007, 19, (1), 15-19.

  • Li, L.; Bading, J.; Yazaki, P. J.; Ahuja, A. H.; Crow, D.; Colcher, D.; Williams, L. E.; Wong, J. Y. C.; Raubitschek, A.; Shively, J. E., A Versatile Bifunctional Chelate for Radiolabeling Humanized Anti-CEA Antibody with In-111 and Cu-64 at Either Thiol or Amino Groups: PET Imaging Of CEA-Positive Tumors with Whole Antibodies.

    Bioconjugate Chemistry 2007, 19, (1), 89-96.

  • Kalman, F. K.; Woods, M.; Caravan, P.; Jurek, P.; Spiller, M.; Tircso, G.; Kiraly, R.; Brucher, E.; Sherry, A. D., Potentiometric and Relaxometric Properties of a Gadolinium-Based MRI Contrast Agent for Sensing Tissue pH.

    Inorganic Chemistry 2007, 46, (13), 5260-5270.

  • Jia, B.; Liu, Z.; Shi, J.; Yu, Z.; Yang, Z.; Zhao, H.; He, Z.; Liu, S.; Wang, F., Linker Effects on Biological Properties of 111In-Labeled DTPA Conjugates of a Cyclic RGDfK Dimer.

    Bioconjugate Chemistry 2007, 19, (1), 201-210.

  • Jeong, W.; Hedrick, J. L.; Waymouth, R. M., Organic Spirocyclic Initiators for the Ring-Expansion Polymerization of β-Lactones.

    Journal of the American Chemical Society 2007, 129, (27), 8414-8415.

  • Hooley, R. J.; Iwasawa, T.; Rebek, J., Detection of Reactive Tetrahedral Intermediates in a Deep Cavitand with an Introverted Functionality.

    Journal of the American Chemical Society 2007, 129, (49), 15330-15339.

  • Hok, S.; Natarajan, A.; Balhorn, R.; DeNardo, S. J.; DeNardo, G. L.; Perkins, J., Synthesis and Radiolabeling of Selective High-Affinity Ligands Designed to Target Non-Hodgkin’s Lymphoma and Leukemia.

    Bioconjugate Chemistry 2007, 18, (3), 912-921.

  • Harris, T. D.; Cheesman, E.; Harris, A. R.; Sachleben, R.; Edwards, D. S.; Liu, S.; Bartis, J.; Ellars, C.; Onthank, D.; Yalamanchili, P.; Heminway, S.; Silva, P.; Robinson, S.; Lazewatsky, J.; Rajopadhye, M.; Barrett, J., Radiolabeled Divalent Peptidomimetic Vitronectin Receptor Antagonists as Potential Tumor Radiotherapeutic and Imaging Agents.

    Bioconjugate Chemistry 2007, 18, (4), 1266-1279.

  • Duval, R. A.; Allmon, R. L.; Lever, J. R., Indium-Labeled Macrocyclic Conjugates of Naltrindole: High-Affinity Radioligands for In Vivo Studies of Peripheral δ Opioid Receptors.

    Journal of Medicinal Chemistry 2007, 50, (9), 2144-2156.

  • Cheng, Z.; Xiong, Z.; Subbarayan, M.; Chen, X.; Gambhir, S. S., 64Cu-Labeled Alpha-Melanocyte-Stimulating Hormone Analog for MicroPET Imaging of Melanocortin 1 Receptor Expression.

    Bioconjugate Chemistry 2007, 18, (3), 765-772.

  • Cable, M. L.; Kirby, J. P.; Sorasaenee, K.; Gray, H. B.; Ponce, A., Bacterial Spore Detection by Tb3+(macrocycle)(dipicolinate) Luminescence.

    Journal of the American Chemical Society 2007, 129, (6), 1474-1475.

  • Ahlgren, S.; Orlova, A.; Rosik, D.; Sandstrom, M.; Sjoberg, A.; Baastrup, B.; Widmark, O.; Fant, G.; Feldwisch, J.; Tolmachev, V., Evaluation of Maleimide Derivative of DOTA for Site-Specific Labeling of Recombinant Affibody Molecules.

    Bioconjugate Chemistry 2007, 19, (1), 235-243.

  • Zarabi, B.; Nan, A.; Zhuo, J.; Gullapalli, R.; Ghandehari, H., Macrophage Targeted N-(2-Hydroxypropyl)methacrylamide Conjugates for Magnetic Resonance Imaging.

    Molecular Pharmaceutics 2007, 3, (5), 550-557.

  • Ye, F.; Ke, T.; Jeong, E.-K.; Wang, X.; Sun, Y.; Johnson, M.; Lu, Z.-R., Noninvasive Visualization of in Vivo Drug Delivery of Poly(l-glutamic acid) Using Contrast-Enhanced MRI.

    Molecular Pharmaceutics 2007, 3, (5), 507-515.

  • Mohsin, H.; Jia, F.; Sivaguru, G.; Hudson, M. J.; Shelton, T. D.; Hoffman, T. J.; Cutler, C. S.; Ketring, A. R.; Athey, P. S.; Simon, J.; Frank, R. K.; Jurisson, S. S.; Lewis, M. R., Radiolanthanide-Labeled Monoclonal Antibody CC49 for Radioimmunotherapy of Cancer: Biological Comparison of DOTA Conjugates and 149Pm, 166Ho, and 177Lu.

    Bioconjugate Chemistry 2007, 17, (2), 485-492.

  • Kumaresan, P. R.; Natarajan, A.; Song, A.; Wang, X.; Liu, R.; DeNardo, G.; DeNardo, S.; Lam, K. S., Development of Tissue Plasminogen Activator Specific “On Demand Cleavable (ODC) Linkers for Radioimmunotherapy by Screening One-Bead-One-Compound Combinatorial Peptide Libraries.

    Bioconjugate Chemistry 2007, 18, (1), 175-182.

  • Kainthan, R. K.; Muliawan, E. B.; Hatzikiriakos, S. G.; Brooks, D. E., Synthesis, Characterization, and Viscoelastic Properties of High Molecular Weight Hyperbranched Polyglycerols.

    Macromolecules 2007, 39, (22), 7708-7717.

  • Harris, T. D.; Kalogeropoulos, S.; Nguyen, T.; Dwyer, G.; Edwards, D. S.; Liu, S.; Bartis, J.; Ellars, C.; Onthank, D.; Yalamanchili, P.; Heminway, S.; Robinson, S.; Lazewatsky, J.; Barrett, J., Structure−Activity Relationships of 111In- and 99mTc-Labeled Quinolin-4-one Peptidomimetics as Ligands for the Vitronectin Receptor: Potential Tumor Imaging Agents.

    Bioconjugate Chemistry 2007, 17, (5), 1294-1313.

  • Gustafsson, B.; Youens, S.; Louie, A. Y., Development of Contrast Agents Targeted to Macrophage Scavenger Receptors for MRI of Vascular Inflammation.

    Bioconjugate Chemistry 2007, 17, (2), 538-547.